Rectification of "USB Pen Drive not opening" problem

It usually happens when your antivirus removes the viruses but references are left to autorun files created by virus and hence when try to open, it shows OPEN with dialog box and "always use this application" box is grayed out.

If content of flash drive is not important then you can format it .

OR

simply open my computer and in address bar type drive letter of your drive, say its M:
then t ype
M:


OR

Goto Run --> type "cmd" then you will get command line,
now type :

Code:

fsutil volume dismount M:


Here M: is your PEN drive letter,

After this try to open your drive normally.